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Understanding Skin Regeneration: The Role of the Epidermis

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Skin Regeneration: How The Epidermis Fits In Our skin is capable of self-renewal, and the part that makes this possible is called the epidermis. It’s a process that is crucial for the healthiness of our skin, and it consists of many important phases.

Cell Production and Migration

This takes place in the basal layer of the epidermis, where new skin cells – primarily keratinocytes – are produced. They migrate upwards through the layers of the epidermis as they mature, undergoing changes in gene expression and biochemistry appropriate for their final role as mechanical barriers. In younger individuals, this journey can last 28–42 days or longer (up to 84 days in older adults due to deceleration of cell turnover)123.

Shedding of Dead Cells

At the surface, they are part of the stratum corneum (dead layer), and eventually will die and desquamate as microscopic flat flakes. This process of shedding is essential as it sloughs away dead skin cells, which if left on the skin cause congestion and other related issues23. This constant regeneration not only restores lost barriers, but it also reinforces the skin barrier against environmental aggression.

Drivers of Renew = Renewal Rates

Epidermal turnover† varies due to various factors such as age, diet hydration and skincare. For example, the skin of younger men turns over cells more quickly than that of older adults and—as a result—probably gets thicker as well due to cell buildup14. Continuing a skin-care regimen that includes mild exfoliation can also help this natural turnover process2.

In short, the epidermis is a very important component of skin health through its renewal process. Understanding this process can help people appreciate how their skincare routine affects the health and appearance of their skin.

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